why do my hands naturally clench?

Israel Palestine
incredible video, close up, indisputable account on the violence of the food aid distribution

DNA
Cells apparently have repair systems to catch and fix DNA mutations?
Also, according to gpt, cells apparently activate "low-fidelity polymerases" (more error prone) under stress as a survival tactic? To increase genetic diversity and in the hopes of survival? How is intention attributed to this phenomena?

• if this is true, then widespread environmental toxicity is rapidly mutating human beings. i wonder how significant it is.
• allegedly this is also the mechanism for bacteria adapting to antibiotics, and tumor cells adapting to chemotherapy. the claim is that they "downregulate DNA repair genes like BRCA1/2 on purpose"
  • read: Rosenberg SM. Evolving responsively: adaptive mutation
  • then find a review
• gpt says the rate difference between induced and spontaneous mutations is 10-1000x
• the thinking is that even though truly useful mutations are rare, the population is so large that these black swan events happen. and since bacteria reproduce quickly and easily, that gene will propagate into a new, thriving, population.

What are the trade-offs with gene duplication? Is another gene then lost?
"So even though the exact mutation is random, where and when mutations happen can be biased." any reviews or papers on this?

Heavy Metals
Arsenic interferes with DNA repair.
ARR3 is an arsenic transporter gene that helps pump arsenic out of a cell. GPT says we can duplicate this gene to help with arsenic toxicity. A possible Gene Editing exploration.

Bay Area Environmentalism
Lead contamination in Oakland

Clean Water
Clean Water#Lead Pipes
apparently low tds water leeches lead from pipes. so whole house water filters that strip minerals can leech more lead.